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Large Volume Parenteral

2025-11-21

LVP is sterile injection liquid into human body by vein, and it volume not less than 50ml.

Main ingredient of LVP:

Water, glucose, amino acid, salt, and viscous nutrient solution.

Now available in the market mainly are four different kind of LVP:

Glucose, NaCl, Glucose/NaCl, Metronidazole

Filtration purpose:

Prefilter: remove the particles, colloid, and extend the working life of fine filters followed.

Fine filter: remove low biological load; sterile filtration

Filtration criteria:

Safety: Filters should be of good mechanical strength, as bottling under high pressure and high speed

Stablity: Filters should provide stable filtration speed and filtration efficiency

Bacterial free: No living bacteria in LVP

Filter System Configurement:

S/N

Stages

Filter Element Recommended

1

Prefilter

TI/STS

2

Prefilter

DPP/IPP/RPP/GF

3

Fine filter

IPS/DHPV

4

Prefilter

DPP/IPP/RPP/GF

5

Final filter

IPS/DHPV

6

Vent

DHPF

Filtration System Diagram:

Large Volume Parenteral.png